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Bone substitutes produced with nanoXIM hydroxyapatite and tricalcium phosphate are biocompatible, osteostimulative and their nanostructure has a remarkable similarity with human bone, being the most promising synthetic material for bone regeneration.

Once placed in the damaged bone area, nanoXIM easily binds to the host tissue and become integrated, inducing the native bone formation and growth. Simultaneously, the graft is resorbed by the natural remodeling process of the bone. In the end, the tissue will be completely reconstructed and the material substituted by native bone.


  • Bone defect

    Bone defect

  • Defect filling with nanoXIM

    Defect filling with nanoXIM

  • material integration and beginning of bone formation

    Material integration and
    beginning of bone formation

  • Dental Sensitivity

    Native bone growth
    and material resorption

  • bone reconstrution

    Bone reconstrution
    / regeneration



  • Injectable Bone Substitutes


  • Bone Scaffolds


  • Prosthesis Coating


  • Prosthesis Coating


  • 3D Printing



Despite the good self-healing capacity of bone, spontaneous healing of bone injury defects larger than a certain size is not possible.

Synthetic materials are able to overcome the disadvantages of the common treatment of bone defects - autologous bone transplantation.

Synthetic materials do not require bone harvesting from the iliac crest, which is connected with significant comorbidity and follow-up operations. Not least is their unlimited availability that eliminates the need to maintain a bone bank and the complicated long-term tissue preservation issues.

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