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FLUIDINOVA develops R&D projects in collaboration with scientific institutes, companies and costumers. 

Currently, our main fields of interest are: 

  • Injectable bone substitutes

    Granules and scaffolds for bone regeneration

    Biomaterials functionalization

  • Enamel remineralization

    Dental hypersensitivity

 

 

 

 

 

Research & Development plays an important role on FLUIDINOVA’s business strategy, helping to provide customers state-of-the-art products.

Therefore, through the years FLUIDINOVA has been involved in several collaborative R&D projects with different European partners as:

 

NEWGEN - New Generation Biomimetic and Customized Implants for Bone Engineering

Start date:   2013-10-02

End date:     2017-10-01

 

Funded by: COST Action MP1301 Materials, Physical And Nanosciences. COST is supported by the EU RTD Framework Programme.

Consortium Partners: FLUIDINOVA, S.A. among more than 70 partners from 21 countries.

 

Objective: This COST Action, NEWGEN, aims at creating the seed for the European research and industry collaboration, combining basic knowledge from academic laboratories, R&D centres, medical units from hospitals, and a significant number of companies.

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IMCOSS - Injectable Medical Ceramics for Bone Repair and Augmentation

Start date:   2012-12-01

End date:     2014-11-30

 

Funded by:   European Community's Seventh Framework Programme under the Research for the Benefit of SMEs Programme.

Consortium Partners: FLUIDINOVA, S.A., Ceramisys Ltd., Primequal SA, The University of Sheffield and Ludwig Boltzmann Gesellschaft – LBI Trauma.

 

Objective: The repair and regeneration of bone tissue remains a significant clinical challenge in many clinical fields including orthopaedics, dentistry, and maxillofacial surgery. The problem is increasing in the face of complicating factors such as the ageing population. The aim of this project is to undertake a basic scientific study of new nanostructured biomaterials that will underpin the development of new nanostructured, injectable bone graft substitutes.

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NanoForBone - Development and scale-up of 3D structures and coatings for medical applications based on nanosized hydroxyapatite

Start date:    2009-02-01

End date:      2012-12-30

 

Funded by:   Agência de Inovação, SA, QREN-sistema de Incentivos à Investigação e Desenvolvimento Tecnológico (SI I&DT), Projecto nº 5372 

Consortium Partners: FLUIDINOVA, S.A., Faculdade de Engenharia do Universidade do Porto and INEB-Instituto de Engenharia Biomédica.

 

Objective:

Development of new products for biomedical applications based on nano Hydroxyapatite raw-materials.

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PILLS - Process Intensification of Liquid Liquid Systems

Start date:    2009-01-01

End date:      2012-03-30

 

Funded by:   European Community's Seventh Framework Programme (FP7/2007-2013) under grant agreement n° NMP2-SL-2008-214599. 

Consortium Partners: FLUIDINOVA, S.A., Huntsman Corp., CUF - Químicos Industriais SA, Givaudan, Chemistry Innovation, Institut für Mikrotechnik Mainz GmbH,University of Coimbra, École Polytechnique Fédérale de Lausanne, Warsaw University of Technology and Britest

 

Objective:

The objective of the PILLS project is to develop and validate a design methodology and criteria for dealing with two-phase liquid/liquid-reactions leading to a new generation of flexible and high-performance process equipment (micro through to meso structured) for continuous manufacturing.

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NETmix-nanoHAp - NETmix reactor for the production of hydroxyapatite nanoparticles 

Start date:    2006-07-01

End date:      2008-06-30

Funded by: Agência de Inovação, SA, PRIME-DEMTEC, Projecto nº 70/00224
Promoter: FLUIDINOVA, S.A. 

Objective:

• Validation of an industrial process – NETmix® technology – for the manufacturing of nano-sized materials;
• Scale up of hydroxyapatite nanoparticles production process – nano-HAp;
• Introduction and demonstration of NETmix® technology to the chemical and pharmaceutical industries.

 

 

 

 

 

 

 

Working closely with research institutions and R&D partners FLUIDINOVA is able to continuously improve its range of products to answer to upcoming market needs while covering a wider spectrum of applications.

FLUIDINOVA has historical links to the Engineering Faculty of the University of Porto (FEUP) and the National Institute for Biomedical Engineering (INEB), concerning the technology development and the focus on calcium phosphate materials.

Nowadays FLUIDINOVA is connected and collaborating with several reference R&D institutions in Europe to expand its know-how and keep up with constant innovation required in the nanomaterials industries.

 

 

 

 

An innovative static mixer photoreactor: Proof of concept

M.J. Lima, A.M.T. Silva, C.G. Silva, J.L. Faria, J.C.B. Lopes, M.M. Dias, “An innovative static mixer photoreactor: Proof of concept”, Chemical Engineering Journal, 287, p. 419 (2016).

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The NETmix reactor: Pressure drop measurementsand 3D CFD modeling

M. Fonte, M. E. Leblebici, M.M. Dias, J.C.B. Lopes, “The NETmix reactor: Pressure drop measurementsand 3D CFD modeling”, Chemical Engineering Research and Design, 91(11), p. 2250 (2013).

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Continuous Production of Magnetic and Metal-Organic Nanoparticles with NETmix Reactor

E. Leblebici, C.M. Fonte, M.F. Costa, F. Ataíde, M.P. Garcia, V. Silva, T. Devic, P. Horcajada, P. Tavares, J.P. Araújo, R. Oliveira, J.L. Faria, M.M. Dias, J.C.B. Lopes, “Continuous Production of Magnetic and Metal-Organic Nanoparticles with NETmix Reactor”  13 AIChE Annual Meeting (2013). 

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The NETmix Reactor: Heat and Mass Transfer Modeling and Mixing Properties Assessment

M. Fonte, M. F. Costa, M. M. Dias, J. C. B. Lopes, “The NETmix Reactor: Heat and Mass Transfer Modeling and Mixing Properties Assessment”, North American Mixing Forum 13 AIChE Annual Meeting (2013)

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NETmix®, a new type of static mixer: experimental characterization and model validation

E. Laranjeira, A.A. Martins, M.I. Nunes, J.C.B. Lopes, M.M. Dias, "NETmix®, a new type of static mixer: experimental characterization and model validation”, AIChE Journal, 57(4), p. 1020-1032 (2011).

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A Highly Reproducible Continuous Process for Hydroxyapatite Nanoparticles Synthesis

P.J. Gomes, V.M.T.M. Silva, P.A. Quadros, M.M. Dias, J.C.B. Lopes, “A Highly Reproducible Continuous Process for Hydroxyapatite Nanoparticles Synthesis”, Journal of Nanoscience and Nanotechnology, 9(6), p. 3387-3395 (2009).

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NETmix®, a new type of static mixer: modeling, simulation, macro and micromixing characterization

E. Laranjeira, A.A. Martins, J.C.B. Lopes, M.M. Dias, "NETmix®, a new type of static mixer: modeling, simulation, macro and micromixing characterization”, AIChE Journal, 55(9), p. 2226-2243 (2009)

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A novel continuous industrial process for producing hydroxyapatite nanoparticles

M.T.M. Silva, P.A. Quadros, P.E.M.S.C. Laranjeira, M.M. Dias, J.C.B. Lopes, “A novel continuous industrial process for producing hydroxyapatite nanoparticles”, Journal of Dispersion Science and Technology, 29, p. 542–547 (2008).

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Network mixer and related mixing process

C.B. Lopes, P.E.M.S.C. Laranjeira, M.M.Q. Dias, A.A.A. Martins, “Network mixer and related mixing process”, PCT/IB2005/000647. European patent EP1720643 (2005)

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